4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐 CAS#: 23307-72-4

微信扫码

4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐

生物活性靶点体外研究体内研究

中文名称	4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐
中文同义词	4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐;((4-氨基苯基)磺酰基)(6-氯吡嗪-2-基)酰胺钠;化合物 SULFACLOZINE SODIUM
英文名称	sodium N-(6-chloropyrazinyl)sulphanilamidate
英文同义词	sodium N-(6-chloropyrazinyl)sulphanilamidate;Sulfaclozine sodium monohydrate;4-Amino-N-(6-chloro-2-pyrazinyl)benzenesulfonamide sodium salt;Sodium ((4-aminophenyl)sulfonyl)(6-chloropyrazin-2-yl)amide;Sulfaclozine (sodium salt)
CAS号	23307-72-4
分子式	C10H10ClN4NaO2S
分子量	308.72
EINECS号	245-571-9
相关类别
Mol文件	23307-72-4.mol
结构式

4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐 性质

4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐 用途与合成方法

生物活性

Sulfaclozine sodium (Sulfachloropyrazine sodium) 是一种有效的磺酰胺衍生物，具有抗菌和抗球虫作用。Sulfaclozine sodium 通常用于各种家禽疾病(尤其是结肠杆菌病，禽霍乱和球虫病)的相关研究。

靶点

Bacterial; Parasite

体外研究

The elimination of Sulfaclozine in the three systems: UV/TiO     ₂    , UV/K     ₂    S     ₂    O     ₈    , and UV/TiO     ₂    /K     ₂    S     ₂    O     ₈    . Sulfaclozine is weakly adsorbed on the surface of TiO     ₂    at pH 7 (< 5%) but efficiently eliminated with the following three systems: UV/TiO     ₂    , UV/K     ₂    S     ₂    O     ₈    , and UV/TiO     ₂    /K     ₂    S     ₂    O     ₈    in ultra pure water. Moreover, 12 of Sulfaclozine by-products are identified and reaction pathways show that, in addition of     ^•    OH and SO     ₄       ^•−    radicals, the conduction-band electrons are responsible for the formation of some main by-products either directly or by the formation of superoxide radicals.

体内研究

Sulfaclozine (60 mg/kg; intravenous injection or oral administration; male broiler chickens) can be used primarily for the treatment of parasitic and microbial infections of the digestive tract rather than for the treatment of systemic infections.

安全信息

MSDS信息

4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐 上下游产品信息