利托那韦EP杂质F 基本信息
中文名称 | 利托那韦EP杂质F |
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中文同义词 | 利托那韦杂质F (EP/BP);RITONAVIR EP杂质F;去(异丙基噻唑基)海因利托那韦;噻唑-5-基甲基((2S,3S,5S)-3-羟基-5-((S)-4-异丙基-2,5-二氧代咪唑啉-1-基)-1,6-二苯基己-2-基)氨基甲酸酯 (利托那韦杂质);利托那韦杂质6(利托那韦EP杂质F);利托那韦EP杂质F;去(异丙基噻唑基)乙内酰脲利托那韦 (>90%) |
英文名称 | Des(isopropylthiazolyl) Hydantoin Ritonavir |
英文同义词 | 1,3-Thiazol-5-ylMethyl N-[(1S,2S,4S)-1-benzyl-2-hydroxy-4-((4S;N-[(1S,2S,4S)-2-Hydroxy-4-[(4S)-4-(1-Methylethyl)-2,5-dioxo-1-iMidazolidinyl]-5-phenyl-1-(phenylMethyl)pentyl]carbaMic Acid 5-ThiazolylMethyl Ester;Ritonavir EP IMpurity F;1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-1-benzyl-2-hydroxy-4-((4S)-4-isopropyl-2,5-dioxoimidazolidin-1-yl)-5-phenylpentyl]carbamate;Ritonavir Impurity 6(Ritonavir EP Impurity F);Ritonavir EP IMP F;Thiazol-5-ylmethyl ((1S,2S,4S)-1-benzyl-4-(((2S)-1-benzyl-2-hydroxy-4-((4S)-4-(1-methylethyl)-2,5-dioxoimidazolidin-1-yl)-5-phenylpentyl)carbamate;Carbamic acid, N-[(1S,2S,4S)-2-hydroxy-4-[(4S)-4-(1-methylethyl)-2,5-dioxo-1-imidazolidinyl]-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester |
CAS号 | 1010809-61-6 |
分子式 | C29H34N4O5S |
分子量 | 550.67 |
EINECS号 | |
相关类别 | 杂质对照品;Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds;Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds |
Mol文件 | 1010809-61-6.mol |
结构式 |
利托那韦EP杂质F 性质
熔点 | 85 - 88°C |
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密度 | 1.277±0.06 g/cm3(Predicted) |
储存条件 | -20°C Freezer |
溶解度 | 可溶于氯仿(少许)、DMSO(少许)、甲醇(少许) |
酸度系数(pKa) | 8.44±0.70(Predicted) |
形态 | 固体 |
颜色 | 白色至类白色 |