中文名: | 金雀异黄酮;金雀异黄酮 |
中文别名: | |
英文名称: | Genistein |
英文别名: | Genistein |
CAS No.: | 446-72-0 |
分子式: | C15H10O5 |
分子量: | 270.24 |
性状: | |
储存: | |
安全术语: | |
风险术语: | |
危险品标志: | |
危险品运输编号: | |
用途: | Genistein is a soy-derived isoflavone and phytoestrogen with antineoplastic activity. Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities. [1]br /[1] http://www.cancer.gov/drugdictionary/?CdrID=43214 |