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![2-(2-(2-(2-(4-(苯并[d]噻唑-2-基)苯氧基)乙氧基)乙氧基)乙氧基)乙醇](https://yunshiji.oss-cn-shenzhen.aliyuncs.com/cas/2274723-90-7.png "2-(2-(2-(2-(4-(苯并[d]噻唑-2-基)苯氧基)乙氧基)乙氧基)乙氧基)乙醇")
![3-碘-2,4,5,6-四氢-1H-环丁烷并[f]茚](https://yunshiji.oss-cn-shenzhen.aliyuncs.com/cas/2271393-82-7.png "3-碘-2,4,5,6-四氢-1H-环丁烷并[f]茚")
| 中文名: | PIK-90;N-(7,8-二甲氧基-2,3-二氢咪唑并[1,2-c]喹唑啉-5-基)烟酰胺 |
| 中文别名: | N-(2,3-二氢-7,8-二甲氧基咪唑并[1,2-C]喹唑啉-5-基)-3-吡啶甲酰胺 |
| 英文名称： | PIK-90 |
| 英文别名： | PIK-90 |
| CAS No.: | 677338-12-4 |
| 分子式: | C18H17N5O3 |
| 分子量: | 351.36 |
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| 用途: | PIK-90 is a potent and cell permeable PI3K inhibitor, with IC50 values (nM) of 11, 350, 18, and 58 for p110 α, β, γ and δ isoforms, low mTOR activity. Besides Val882 H-binding, PIK-90 uses its pyridine ring to enter the hydrophobic affinity pocket of the ATP binding site, where it also interacts with Lys833. |
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