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| 中文名: | 伊帕瑞林;伊帕瑞林 |
| 中文别名: | |
| 英文名称： | Ipamorelin |
| 英文别名： | Ipamorelin |
| CAS No.: | 170851-70-4 |
| 分子式: | C40H53N9O7 |
| 分子量: | 771.86 |
| 性状: | |
| 储存: | |
| 安全术语: | |
| 风险术语: | |
| 危险品标志: | |
| 危险品运输编号: | |
| 用途: | Ipamorelin is a selective growth hormone secretagogue and agonist of the ghrelin receptor. [1] In pentobarbital anaesthetised rats, ipamorelin released GH with a potency and efficacy comparable to GHRP-6 (ED50 = 80±42 nmol/kg and Emax = 1545±250 ng GH/ml vs 115±36nmol/kg and 1167±120ng GH/ml). In conscious swine, ipamorelin released GH with an ED50 = 2.3±0.03 nmol/kg and an Emax = 65±0.2 ng GH/ml plasma. Again, this was very similar to GHRP-6 (ED50 = 3.9±1.4 nmol/kg and Emax = 74±7ng GH/ml plasma). GHRP-2 displayed higher potency but lower efficacy (ED50 = 0.6 nmol/kg and Emax = 56±6 ng GH/ml plasma). The specificity for GH release was studied in swine.br /[1] Venkova K et al. J Pharmacol Exp Ther. 2009 Jun;329(3):1110-6 |
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