中文名: | 尼可地尔;硝烟酯, 一种钾离子通道激活剂 |
中文别名: | |
英文名称: | Nicorandil(Ikorel) |
英文别名: | Nicorandil(Ikorel) |
CAS No.: | 65141-46-0 |
分子式: | C8H9N3O4 |
分子量: | 211.17 |
性状: | |
储存: | |
安全术语: | |
风险术语: | |
危险品标志: | |
危险品运输编号: | |
用途: | Nicorandil(Ikorel)is potassium channel activator. It acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It does this through two methods. Firstly, by activating potassium channels, and secondly by donating nitric oxide to activate the enzyme guanylate cyclase. Guanylate cyclase causes activation of cGMP leading to both arterial and venous vasodilatation by de-phosphorylation of the myosin light chain. [1] br /[1] http://en.wikipedia.org/wiki/Nicorandil |