详细说明
别名: Interleukin-1 receptor alpha Interleukin-1 receptor type I RI Serpin F1
产品名称
Other Notes
Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.
Reconstitution
Reconstitute with 50 μL deionized water.
Physical form
Lyophilized from PBS.
General description
IL-1RI is the receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88, and IRAK1 or IRAK2.
性质
| recombinant | expressed in HEK 293 cells |
| assay | >95% (SDS-PAGE) |
| form | lyophilized |
| mol wt | mol wt ~80 kDa by SDS-PAGE |
| impurities | <0.1 EU/μg endotoxin, tested |
| shipped in | wet ice |
| storage temp. | ?20°C |
| Gene Information | human ... IL1R1(3554) |
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