详细说明
别名: IL17E IL25 InterleukinE
MDL number MFCD05665417
产品名称
General description
IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NK-kB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains.
Reconstitution
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstituted in water to a concentration of 0.1 μg/μL.
Physical form
Lyophilized with no additives.
性质
recombinant | expressed in E. coli |
assay | ≥98% (HPLC) |
≥98% (SDS-PAGE) | |
form | lyophilized |
mol wt | mol wt ~33.8 kDa |
impurities | endotoxin, tested |
NCBI accession no. | Q9H293 |
shipped in | wet ice |
storage temp. | ?20°C |
Gene Information | human ... IL25(64806) |