详细说明
别名: ACT-2 CCL4L1 HC21 Lymphocyte Activation Gene-1 T-cell activiation-2
产品名称
Biochem/physiol Actions
LAG-1 is CC chemokine that signals through the CCR5 receptor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues.
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Physical form
Lyophilized with no additives.
General description
LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1beta (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues.
Sequence
APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN
性质
recombinant | expressed in E. coli |
assay | ≥98% (HPLC) |
≥98% (SDS-PAGE) | |
form | lyophilized |
mol wt | mol wt 7.7 kDa |
impurities | <0.1 EU/μg endotoxin, tested |
suitability | cell culture tested |
UniProt accession no. | Q8NHW4 |
shipped in | wet ice |
storage temp. | ?20°C |
Gene Information | human ... CCL4L1(9560) |