详细说明
别名: CCL16 LCC-1 LMC Liver-Expressed Chemokine MTN-1 NCC-4
产品名称
Biochem/physiol Actions
LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. Recombinant human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Physical form
Lyophilized with no additives.
General description
LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes but not neutrophils. Recombinant human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Sequence
QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ
性质
recombinant | expressed in E. coli |
assay | ≥98% (HPLC) |
≥98% (SDS-PAGE) | |
form | lyophilized |
mol wt | mol wt 11.2 kDa |
impurities | <0.1 EU/μg endotoxin, tested |
suitability | cell culture tested |
UniProt accession no. | O15467 |
shipped in | wet ice |
storage temp. | ?20°C |
Gene Information | human ... CCL16(6360) |