别名:   CXCL12 PBSF

产品名称

Biochem/physiol Actions

SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. Recombinant human SDF-1α is an 8.0 kDa protein containing 68 amino acid residues. Recombinant human SDF-1β is an 8.5 kDa protein containing 72 amino acid residues.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Physical form

Lyophilized with no additives.

General description

SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor.

性质

recombinant	expressed in E. coli
assay	≥98% (HPLC)
	≥98% (SDS-PAGE)
form	lyophilized
mol wt	mol wt 8.5 kDa
impurities	<0.1 EU/μg endotoxin, tested
UniProt accession no.	P48061
shipped in	wet ice
storage temp.	?20°C
Gene Information	human ... CXCL12(6387)