别名:   IFN-γ

•  MDL number  MFCD00131391

• Popular Documents:  Datasheet (PDF)  |  Specification Sheet (PDF)

产品名称

Analysis Note

The biological activity of recombinant mouse IFN-γ is measured by its ability to inhibit the proliferation of murine WEHI-279 cells.

Physical form

Lyophilized from a 0.2 μm filtered buffered solution. Package size based on protein content.

Application

Interferon-γ from mouse has been used:
? for in vitro stimulation of the BMDC (bone marrow derived dendritic cell), BMM (bone marrow-derived macrophages) and CD11c⁺ (CD11 antigen-like family member C) lung macrophages
? for stimulation of murine macrophages to induce the production of nitrite and nitrate
? to check CCAAT/enhancer binding protein β (C/EBPβ)-mediated changes in the expression of prostaglandin synthesis enzymes in neuroinflammation

Biochem/physiol Actions

Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections.

性质