Biochem/physiol Actions

Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.

L-glutamate plays key roles in development, learning, memory, plasticity and cognition. It plays crucial role in the pathogenesis of neuropathological diseases such as epilepsy, schizophrenia, stroke, ischemia, ALS (amyotrophic lateral sclerosis), Huntington’s disease and Parkinson’s disease. Glutamate is also responsible for the activation of long-term potentiation (LTP) and long-term depression (LTD). Induction of glutamate receptors plays a key role in the pathophysiology of migraine.

包装

1 kg in poly bottle

100, 500 g in poly bottle

Application

L-Glutamic acid potassium salt monohydrate has been used-
? for the purification of tubulins from bovine brain
? in stock solution for the preparation of quenching buffer during the formationof dual-color polarity-marked fluorescent microtubule seeds
? the preparation of cell free extracts devoid of RF2 (release factor 2) from Escherichia coli strains
? preparation of stock solutions during culture of Arabidopsis plants

General description

L-glutamate is the major excitatory neurotransmitter in mammalian central nervous system (CNS). It interacts with membrane bound glutamate receptors.