重组人IL-31 10 UG

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  • 更新2024-11-20 03:29
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DMEM/无糖培养基(含谷氨酰胺,不含HEPES、葡萄糖、丙酮酸钠、酚红) 500ml/瓶 DMEM/高糖培养基(含高糖、稳定的谷氨酰胺、酚红,不含丙酮酸钠、HEPES) 500ml/瓶 DMEM/高糖培养基(含高糖、L-谷氨酰胺、酚红,不含丙酮酸钠、HEPES、磷酸) 500ml/瓶 DMEM/高糖培养基(含高糖、L-谷氨酰胺、HEPES、酚红、双抗,不含丙酮酸钠) 500ml/瓶 DMEM/高糖培养基(含高糖、稳定的谷氨酰胺、酚红、丙酮酸钠,不含HEPES) 500ml/瓶 DMEM/高糖培养基(含高糖、稳定的谷氨酰胺、酚红、HEPES,不含丙酮酸钠) 500ml/瓶

产品介绍

    基本参数

    详细说明

    产品描述

    概述

    Human IL-31 gene is located on Chr.12. It expresses the IL-31 protein at low levels in the type 2 helper T cells, which exits in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea. This protein shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. IL-31 signals through IL-31 receptor A and oncostatin M receptor subunits and can activate STAT3 through receptors and maybe involve in skin immunity. It regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Human IL-31 shares 24 % a.a. sequence identity in the mature protein with mouse IL-31.

    使用说明

    This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

    技术规格

    Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
    Purity> 97 % by SDS-PAGE and HPLC analyses.
    SourceEscherichia coli.
    Biological ActivityFully biologically active when compared to standard. The specific activity is determined by inducing STAT3 activation using human U-87 MG cells. 5 ng/mL of rHuIL-31 can effectively induce STAT3 activation.
    FormulationLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH7.4.
    EndotoxinLess than 1 EU/μg of rHuIL-31 as determined by LAL method.
    ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
    AA SequenceSHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T

    其它别名:IL-31, Human储存:冷冻(-20℃)分子量:Approximately 15.8 kDa, a single non-glycosylated polypeptide chain containing 141 amino acids.

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