生物来源

human

重组

expressed in E. coli

测定

≥98% (SDS-PAGE)

形式

lyophilized powder

分子量

9.72 kDa

包装

pkg of 10 and 50 μg

杂质

<1 EU/μg endotoxin (LAL test)

UniProt登记号

Q9NPD7

运输

wet ice

储存温度

−20°C

Gene Information

human ... NRN(51299)

相关类别

Growth Factors and Cytokines

一般描述

Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in post mitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation. Recombinant human Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.72 kDa polypeptide monomers, each containing 88 amino acid residues.

外形

Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.

重悬

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.