产品编号:

250-16

别名:

纬-Interferon Inducible Protein-10, CXCL10, crg-2

描述:

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant Murine IP-10 is an 8.7 kDa protein consisting of 77 amino acids, including the four conserved cysteine residues present in CXC chemokines.

氨基酸序列:

IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

Assay #1:Determined by its ability to chemoattract IL-2 activated T cells using a concentration range of 0.1-10.0 ng/ml.
Assay #2: Determined by its ability to chemoattract CXCR3-transfected HEK293 cells using a concentration range of 100-500 ng/ml.

交叉反应:

Bacteria, Human, Mouse, Rat, Monkey

原产国:

USA