产品编号:

300-14

别名:

Neutrophil Activating Protein-2, CXCL7, PBP (parent molecule), CTAP-III (precursor)

描述:

NAP-2 is a CXC chemokine that can signal through the CXCR1 and CXCR2 receptors.  It is produced in leukocytes by enzymatic processing of a precursor called platelet basic protein (PBP).  NAP-2 chemoattracts and activates neutrophils.  Recombinant Human NAP-2 protein is a 7.6 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines, and also the 鈥淓LR鈥?motif, common to CXC chemokines that bind to CXCR1 and CXCR2.

氨基酸序列:

AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDESAD

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

Determined by its ability to chemoattract human neutrophils using a concentration range of 1.0-10.0 ng/ml.

交叉反应:

Bacteria, Hamster, Human, Mouse

原产国:

USA