详细说明
Replacement Information |
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描述 | |
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产品目录编号 | MPC4NTR10 |
商名 |
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描述 | MultiScreen 渗透性,3.0 µm,非无菌 |
背景信息 | Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates. MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport. Membranes have uniform pore structure and density for reliable transport: - Individual wells minimize candidate cross-talk - Compatibility with automated liquid handling systems increases throughput Permeability Assay: - The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1 PAMPA Assay: - The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3 MultiScreen Acceptor Plate: - The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated. |
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产品信息 | |
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自动化兼容性 | No |
过滤器代码 | PCF |
色码 | 透明 |
孔数 | 96 |
应用 | |
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应用 | 通透性研究 |
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生物信息 | |
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无菌性 | 非无菌 |
理化信息 | |
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孔径 | 0.4 µm |
尺寸 | |
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体积 | 100 µL |
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产品使用声明 |
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包装信息 | |
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数量 | 10 |
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