同义词：   SRT 1720 Hydrochloride; N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamide hydrochloride  

应用；   A selective SIRT1 activator  

CAS号码:   1001645-58-4  

纯度:   ≥98%  

分子量:   506.02  

分子式:   C₂₅H₂₃N₇OS•HCl  

* Refer to Certificate of Analysis for lot specific data (including water content).

介绍 技术信息 安全信息 安全技术说明书和分析证明书

SRT1720 is an NAD-dependent deacetylase sirtuin-1 (SIRT1) activator (EC₅₀ = 0.16 μM), highly selective for SIRT1 over SIRT2 or SIRT3. Studies in yeast suggest that sirtuins may be involved in epigentic gene silencing and deactylation of proteins that regulate the cell cycle.

外观 :

Powder

物理状态 :

Solid

溶解度 :

Soluble in water (< 1 mg/mL at 25 °C), DMSO (38 mg/mL at 25 °C), and ethanol (< 1 mg/mL at 25 °C).

保存 :

Store at -20° C

熔点 :

209 °C

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.  

PubChem CID :

25232708

SMILES :

C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl