同义词：   4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid  

应用；   An antibiotic which induces mitochondrial permeability pore opening  

CAS号码:   518-75-2  

分子量:   250.25  

分子式:   C₁₃H₁₄O₅  

Supplemental Information:   This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.  

* 参考分析证明 大量特定数据 (包括水 含量).

介绍 技术信息 安全信息 安全技术说明书和分析证明书

Citrinin is an antibiotic which induces mitochondrial permeability pore opening and inhibits respiration by interfering with complex I of the respiratory chain. Mycotoxin acting as nephrotoxin in all species in which has been tested. Also induces apoptosis.

物理状态 :

Solid

溶解度 :

Soluble in 100% ethanol, methanol, dichlormethane, and DMSO. Insoluble in water.

保存 :

Store at -20° C

熔点 :

177.49° C (Predicted)

沸点 :

440.63° C at 760 mmHg (Predicted)

密度 :

1.38 g/cm    ³ (Predicted)

折射率 :

n    ²⁰    _D 1.60 (Predicted)

IC50 :

HL-60 : IC    ₅₀ = >10 µM (human); KB : IC    ₅₀ = >10 µM (human); HCT-116: IC    ₅₀ = >10 µM (human); Amaranthus hypochondriacus: IC    ₅₀ = 55 µM; Echinochloa crus-galli: IC    ₅₀ = 63 µM

Ki 数据 :

OAT3: K    _i= 15.4 µM (human); SLC22A11: K    _i= 366.4 µM (human); OAT1: K    _i= 3080 µM (human)

pK值 :

pK    _a: 1.52 (Predicted)

仅供科研使用。不可用于诊断或治疗。  

德国水公害等级 :

3

RTECS :

DJ2275000

运输 :

UN 3462, Class 6.1, Packing group III

PubChem CID :

54680783

默克索引 :

14: 2327

MDL 号码 :

MFCD00006912

EC号码 :

208-257-2

Beilstein 注册 :

5282243

SMILES :

C[C@@H]1[C@H](OC=C2C1=C(C(=C(C2=O)C(=O)O)O)C)C