详细说明
应用; A histamine release and calcium flux augmenter
CAS号码: 71774-08-8
分子量: 336.47
分子式: C20H32O4
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* 参考分析证明 大量特定数据 (包括水 含量).
介绍 技术信息 安全信息 安全技术说明书和分析证明书
5(S)-HPETE is a monohydroperoxy polyunsaturated fatty acid produced by 5-lipoxygenase metabolism of arachidonic acid and a biosynthetic precursor to leukotrienes. 5(S)-HPETE is described to induce c-fos without inducing c-jun in TA1 cells, suggesting that c-fos induction by TNF may be HPETE-mediated. 5(S)-HPETE is also described to modulate histamine release from human basophils.
参考文献
1. Naccache, P.H., et al. 1981. J. Clin. Invest. 67: 1584-1587. PMID: 6262382
2. Peters, S.P., et al. 1981. Nature. 292: 455-457. PMID: 6166867
3. Haliday, E.M., et al. 1991. EMBO J. 10: 109-115. PMID: 1899225
4. Levery, S.B., et al. 1994. Arch. Biochem. Biophys. 312: 125-134. PMID: 8031119
规划 :
50 µg/ml in ethanol
外观 :
Oil dissolved in ethanol
物理状态 :
Liquid
溶解度 :
Soluble in ethanol
保存 :
Store at -80° C
沸点 :
78° C
仅供科研使用。不可用于诊断或治疗。
运输 :
UN 1170, Class 3, Packing group II
PubChem CID :
5280778
SMILES :
CCCCCC=CCC=CCC=CC=CC(CCCC(=O)O)OO