同义词：   6-Bromolevamisole oxalate  

应用；   A non-specific alkaline phosphatase inhibitor  

CAS号码:   62284-79-1  

纯度:   ≥98%  

分子量:   373.22  

分子式:   C₁₁H₁₁BrN₂S•C₂H₂O₄  

* 参考分析证明 大量特定数据 (包括水 含量).

介绍 技术信息 安全信息 安全技术说明书和分析证明书

L-p-Bromotetramisole (Oxalate) is an inhibitor of non-specific alkaline phosphatase, comparable in activity to the vanadium compound Orthovanadate (sc-3540). L-p-Bromotetramisole shows no inhibition of specific phosphatase activity, and the D- enantiomer shows no inhibitory effects against either phosphatase. The activity of tyrosine phosphatases is also reported to be inhibited by L-p-Bromotetramisole and related compounds.

参考文献

1. Borgers, M. and Thoné, F. 1975. Histochemistry. 44: 277-280. PMID: 171243
2. Borgers, M. and Thoné, F. 1976. Histochem. J. 8: 301-317. PMID: 59721
3. Swarup, G., et al. 1982. J. Biol. Chem. 257: 7298-7301. PMID: 6282838
4. Kuwana, T. and Rosalki, S.B. 1991. J. Clin. Pathol. 44: 236-237. PMID: 2013625
5. Kovach, J.S., et al. 1992. J. Natl. Cancer Inst. 84: 515-519. PMID: 1312177

外观 :

Powder

物理状态 :

Solid

溶解度 :

Soluble in water (25 mg/ml), DMF, DMSO, and methanol.

保存 :

Store at 4° C

熔点 :

192° C (lit.)(dec.)

光学活性 :

α25/D -105°, c = 0.5 in water

pK值 :

pK    _b: 9.80

仅供科研使用。不可用于诊断或治疗。  

德国水公害等级 :

3

PubChem CID :

2724023

MDL 号码 :

MFCD00070406

EC号码 :

263-487-0

Beilstein 注册 :

4944883

SMILES :

C1CSC2=N[C@H](CN21)C3=CC=C(C=C3)Br.C(=O)(C(=O)O)O