详细说明
Species Reactivity
Mouse
Specificity
Detects mouse CCR10. Stains mouse CCR10-transfected cells but not irrelevant transfectants.
Source
Monoclonal Rat IgG 2B Clone # 248918
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
C6 rat glioma cell line transfected with mouse CCR10
Met1-Asn362
Accession # NP_031747Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Phycoerythrin
Applications
Recommended
ConcentrationSample
Flow Cytometry
10 µL/10 6 cells
See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. are available in the Technical Information section on our website.
Data Examples
Flow Cytometry | Detection of CCR10 in B16‑F1 Mouse Cell Line by Flow Cytometry. B16‑F1 mouse melanoma cell line was stained with Rat Anti-Mouse CCR10 PE‑conjugated Monoclonal Antibody (Catalog # FAB2815P, filled histogram) or isotype control antibody (Catalog # , open histogram). View our protocol for . |
Flow Cytometry | Detection of CCR10 in BaF3 Mouse Cell Line Transfected with CCR10 and eGFP by Flow Cytometry. BaF3 mouse pro-B cell line transfected with mouse CCR10 and eGFP was stained with Rat Anti-Mouse CCR10 PE‑conjugated Monoclonal Antibody (Catalog # FAB2815P) and. Quadrant markers were set based on control antibody staining (Catalog # ). dView our protocol for . |
Preparation and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
Background: CCR10
CCR10 is a G protein-linked seven transmembrane domain protein expressed by T cells and B cell subsets that functions as a receptor for CCL27. CCR10 mediates lymphocyte migration to the skin and mucosa, and its expression correlates with the metastatic capacity of melanomas.
Entrez Gene IDs:
2826 (Human); 12777 (Mouse); 363682 (Rat)
Alternate Names:
CC chemokine receptor 10; C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR10; CCR-10; chemokine (C-C motif) receptor 10; G protein-coupled receptor 2; GPR2; GPR2G-protein coupled receptor 2