Mouse DNER MAb (Clone 298306) 25 UG

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Mouse DNER MAb (Clone 298306) 25 UG信息二维码

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产品介绍

    基本参数

    详细说明

    • Species Reactivity

      Mouse

    • Specificity

      Detects mouse DNER in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human DNER is observed.

    • Source

      Monoclonal Rat IgG    1 Clone # 298306

    • Purification

      Protein A or G purified from hybridoma culture supernatant

    • Immunogen

      Mouse myeloma cell line NS0-derived recombinant mouse DNER    
      Ala26-His637    
      Accession # Q8JZM4

    • Formulation

      Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

    • Label

      Unconjugated

    Applications

    • Recommended    
      Concentration

      Sample

    • Western Blot

      1 µg/mL

      Recombinant Mouse DNER under non-reducing conditions only


    • Immunohistochemistry

      8-25 µg/mL

      Perfusion fixed frozen sections of mouse brain (cerebellum)


    Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

    Preparation and Storage

    • Reconstitution

      Reconstitute at 0.5 mg/mL in sterile PBS.

    • Shipping

      The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

    • Stability & Storage

      Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

      • 12 months from date of receipt, -20 to -70 °C as supplied.

      • 1 month, 2 to 8 °C under sterile conditions after reconstitution.

      • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

    Background: DNER

    DNER, also known as BET, is a type I transmembrane glycoprotein that is specifically expressed on nonaxonal areas of post-mitotic neurons. The protein has an extracellular domain containing ten distinct EGF-like repeats similar to those found on Delta and Notch.

    • Long Name:

      Delta/Notch-like EGF Repeat-containing Transmembrane

    • Entrez Gene IDs:

      92737 (Human); 227325 (Mouse)

    • Alternate Names:

      bet; delta and Notch-like epidermal growth factor-related receptor; delta/notch-like EGF repeat containing; delta-notch-like EGF repeat-containing transmembrane; DNER; H_NH0150O02.1; UNQ26; WUGSC:H_NH0150O02.1



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