• Species Reactivity

  Canine

• Specificity

  Detects canine CD44.

• Source

  Monoclonal Mouse IgG    ₁ Clone # 69-S5

• Purification

  Protein A or G purified from hybridoma culture supernatant

• Immunogen

  Canine marrow cells    
  Accession # Q28284

• Formulation

  Supplied in a saline solution containing BSA and Sodium Azide.

• Label

  Allophycocyanin

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  10 µL/10    ⁶ cells

  See below

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Data Examples

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Protect from light.    Do not freeze.    

• 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD44

Canine CD44 (also known as HCAM and Hermes) is a ubiquitously expressed 85‑90 kDa type I transmembrane glycoprotein that binds to hyaluronan, laminin, fibronectin, selectins, osteopontin, and chondroitin sulfate, and is involved in matrix adhesion, lymphocyte activation, and lymph node homing. The CD44 protein is expressed as a family of molecular isoforms that, in human and presumably in canine, are generated by alternative splicing and variable posttranslational modification. It is reported to form a complex with CD147. Within the N‑terminal invariant portion of the ECD (aa 14‑191), canine CD44 shares 90%, 83%, and 82% identity with human, mouse, and rat CD44, respectively.

• Entrez Gene IDs:

  960 (Human); 12505 (Mouse); 25406 (Rat); 100126860 (Porcine)

• Alternate Names:

  CD44 antigen; CD44 molecule (Indian blood group); CD44; CD44R; CDw44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMR-III; epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCAM; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HUTCH-I; Hyaluronate receptor; IN; LHR; MC56; MDU2; MDU2CD44 antigen (homing function and Indian blood group system); MDU3; MDU3CDW44; MIC4; MIC4MGC10468; MUTCH-I; Pgp1; PGP-1; PGP-I; Phagocytic glycoprotein 1; Phagocytic glycoprotein I