详细说明
Accession #
HRP2294 |
| |
Formulation Supplied as a 0.2 μM filtered solution in phosphate-buffered saline (PBS) with stabilizers and preservatives. | ||
Stability & Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Background: Pin1
Pin1 is a peptidyl-prolyl isomerase (PPI) that targets phosphorylated serine or threonine residues followed by a proline (S/T-P). Isomerization of phosphorylated serine or threonine residues may alter protein confirmation and, subsequently, modify activity. Pin1 is overexpressed in many human breast cancers and has been shown to modify numerous proteins, including p53, NF-kB, c-Jun, cyclin D1, and beta-catenin.
Long Name:
Protein [Peptidyl-prolyl cis/trans Isomerase] NIMA-interacting 1
Entrez Gene IDs:
5300 (Human)
Alternate Names:
dod; EC 5.2.1.8; peptidylprolyl cis/trans isomerase, NIMA-interacting 1; peptidyl-prolyl cis/trans isomerase, NIMA-interacting; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; Pin1; PPIase Pin1; prolyl isomerase; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1; Rotamase Pin1; UBL5
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