• Species Reactivity

  Human

• Specificity

  Detects human STRA6 in direct ELISAs.

• Source

  Monoclonal Mouse IgG1 Clone # 496613

• Immunogen

  NS0 mouse myeloma cell line transfected with human STRA6    
  Met1-Pro667    
  Accession # AAH25256

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 405

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Intracellular Staining by Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  HT‑29 human colon adenocarcinoma cell line fixed with paraformaldehyde and permeabilized with saponin

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: STRA6

Stimulated by retinoic acid gene 6 protein homolog (STRA6) is a 74 kDa broadly expressed transmembrane protein that does not belong to any particular family of proteins. Human STRA6 is 667 amino acids (aa) in length. It contains nine transmembrane regions and one potential N-linked glycosylation site in the first extracellular domain. In addition, there are three splicing variants producing four isoforms. There is no signal sequence. Human STRA6 is 80% identical to bovine STRA6 and 74% identical to mouse and rat STRA6. STRA6 may act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Defects in STRA6 are the cause of Spear syndrome and Matthew-Wood syndrome.

• Long Name:

  Stimulated by Retinoic Acid Gene 6 Protein Homolog

• Entrez Gene IDs:

  64220 (Human); 20897 (Mouse)

• Alternate Names:

  FLJ12541; MCOPS9; stimulated by retinoic acid gene 6 homolog (mouse); stimulated by retinoic acid gene 6 protein homolog; STRA6