• Species Reactivity

  Human

• Specificity

  Detects human CCK‑A R. Stains human CCK-A R transfectants but not irrelevant transfectants.

• Source

  Monoclonal Mouse IgG2a Clone # 377251

• Immunogen

  NS0 mouse myeloma cell line transfected with human CCK‑A R    
  Met1-Gln428    
  Accession # P32238

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 405

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  Human CCK‑A R transfected cells

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CCK-A R

Cholecystokinin A Receptor (CCK-A R) is one of two 7TM receptors for cholecystokinin peptide hormones. This GPCR is involved in gallbladder contraction, insulin secretion, and central nervous system function. CCK-A R has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction. Human CCK-A R shares 89% aa sequence identity with mouse and rat CCK-A R.

• Long Name:

  Cholecystokinin Receptor, Type A

• Entrez Gene IDs:

  886 (Human); 12425 (Mouse)

• Alternate Names:

  CCK1R; CCK1-R; CCK-A R; CCK-A receptor; CCK-A; CCKAR; CCK-AR; CCKRA; cholecystokinin A receptor; cholecystokinin receptor type A; cholecystokinin type-A receptor; Cholecystokinin-1 receptor