• Species Reactivity

  Human

• Specificity

  Stains human GPR34 transfectants but not irrelevant transfectants.

• Source

  Monoclonal Mouse IgG2a Clone # 419859

• Immunogen

  NS0 mouse myeloma cell line transfected with human GPR34    
  Accession # Q9UPC5

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 700

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Intracellular Staining by Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  A172 human glioblastoma cell line fixed with paraformaldehyde and permeabilized with saponin

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: GPR34

GPR34 is a widely expressed 75-90 kDa seven transmembrane segment glycoprotein. It is upregulated on microglia during inflammation and functions as a receptor for lysophosphatidyl-L-serine on mast cells to promote degranulation. Multiple isoforms of GPR34 may result from multiple translation initiation sites and alternative splicing. Human GPR34 shares 89% amino acid sequence identity with mouse and rat GPR34.

• Long Name:

  G Protein-coupled Receptor 34

• Entrez Gene IDs:

  2857 (Human); 23890 (Mouse); 554353 (Rat)

• Alternate Names:

  G protein-coupled receptor 34; GPR34; probable G-protein coupled receptor 34