• Species Reactivity

  Human

• Specificity

  Detects human ENPP‑3/CD203c.

• Source

  Monoclonal Mouse IgG1 Clone # NP4D6

• Immunogen

  HEK293 human embryonic kidney cell line transfected with human ENPP‑3/CD203c    
  Accession # O14638

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 488

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  Human whole blood lymphocytes and monocytes

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: ENPP-3/CD203c

CD203c is a 150 kDa type II transmembrane glycoprotein with a short cytoplasmic tail. CD203c is also known as ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP-3) and modulates purinergic signaling by hydrolysis of nucleotide triphosphates. CD203c is expressed on activated basophils and mast cells during allergic reactions, cardiac muscle, hepatocytes, and epithelial cells. It is upregulated in colon and bile duct carcinomas. Within the ECD, human CD203c shares 81% aa sequence identity with mouse and rat CD203.

• Long Name:

  Ectonucleotide Pyrophosphatase/Phosphodiesterase 3

• Entrez Gene IDs:

  5169 (Human)

• Alternate Names:

  B10; CD203c antigen; CD203c; dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3); dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3); ectonucleotide pyrophosphatase/phosphodiesterase 3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3; E-NPP 3; ENPP3; ENPP-3; gp130RB13-6; NPP3; PD-IBETA; PDNP3; PDNP3B10; Phosphodiesterase I beta; Phosphodiesterase I/nucleotide pyrophosphatase 3; phosphodiesterase-I beta