详细说明
- Species ReactivityHuman
- SpecificityDetects human CD160 in direct ELISAs. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse CD160 is observed.
- SourceMonoclonal Mouse IgG2b Clone # 688327
- ImmunogenChinese hamster ovary cell line CHO-derived recombinant human CD160
Ile27-Ser159
Accession # O95971 - FormulationSupplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
- LabelAlexa Fluor 350
- Recommended
ConcentrationSample
- Flow Cytometry0.25-1 µg/10 6 cellsHuman peripheral blood lymphocytes
- ShippingThe product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
- Stability & StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date.
V‑type Ig-like domain (aa 27-122). CD160 is found as a soluble, disulfide-linked 80 kDa multimer (likely trimer) that is generated by proteolysis of the GPI-linked form. This 80 kDa form, plus others, are highly resistant to reduction. There is also a 100-110 kDa multimeric transmembrane (TM) form that is associated with activated NK cells. It contains a 55 aa substitution for Gly180-Leu181, and shows a 20 aa TM segment between aa 163-182. The TM form appears to have a splice variant that lacks aa 25-133. Over aa 27-159, human CD160 shares 62% aa identity with mouse CD160.
- Entrez Gene IDs:11126 (Human); 54215 (Mouse); 502585 (Rat)
- Alternate Names:BY55; BY55FLJ46513; CD160 antigenimmunoglobulin superfamily member; CD160 molecule; CD160; Natural killer cell receptor BY55; NK1; NK28