• Species Reactivity

  Human

• Specificity

  Detects human CD39L1 in direct ELISAs and Western blots.  In direct ELISAs, approximately 40% cross-reactivity with recombinant mouse CD39L1 and less than 1% cross-reactivity with recombinant human (rh) CD39L2, rhCD39L3, and rhCD39L4 is observed.

• Source

  Polyclonal Sheep IgG

• Purification

  Antigen Affinity-purified

• Immunogen

  Chinese hamster ovary cell line CHO-derived recombinant human CD39L1/ENTPD2    
  Thr29-Asp460    
  Accession # Q9Y5L3

• Formulation

  Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

• Label

  Unconjugated

Applications

• Recommended    
  Concentration

  Sample

• Western Blot

  1 µg/mL

  See below

• 
  

• Immunoprecipitation

  25 µg/mL

  Conditioned cell culture medium spiked with Recombinant Human CD39L1/ENTPD2 (Catalog # ),

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Data Examples

Preparation and Storage

• Reconstitution

  Sterile PBS to a final concentration of 0.2 mg/mL.

• Shipping

  The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

• Stability & Storage

  Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

• 12 months from date of receipt, -20 to -70 °C as supplied.

• 1 month, 2 to 8 °C under sterile conditions after reconstitution.

• 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CD39L1/ENTPD2

CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells (1). CD39L1 is a Ca²⁺ and Mg²⁺ dependent enzyme that activates platelets by preferentially converting ATP to ADP (2). CD39L1 plays a role in regulating thrombosis and inflammation (3). It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation (2, 4).

• References:

• Long Name:

  Ecto-Nucleoside Triphosphate Diphosphohydrolase 2

• Entrez Gene IDs:

  954 (Human); 12496 (Mouse)

• Alternate Names:

  CD39 antigen-like 1; CD39L1; CD39L1NTPDase 2; CD39-like-1; EC 3.6.1; EC 3.6.1.-; EC 3.6.1.5; Ecto-ATP diphosphohydrolase 2; Ecto-ATPase 2; Ecto-ATPase; Ecto-ATPDase 2; ectonucleoside triphosphate diphosphohydrolase 2; ENTPD2; NTPD2; NTPDase 2; NTPDase-2