• Species Reactivity

  Mouse

• Specificity

  Detects mouse TREM-3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross‑reactivity with recombinant mouse (rm) TREM-2b and rmTREM-1 is observed.

• Source

  Polyclonal Goat IgG

• Purification

  Antigen Affinity-purified

• Immunogen

  Mouse myeloma cell line NS0-derived recombinant mouse TREM-3    
  Gly20-Pro135    
  Accession # NP_067382

• Formulation

  Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

• Label

  Unconjugated

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Western Blot

  0.1 µg/mL

  Recombinant Mouse TREM‑3

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Reconstitution

  Reconstitute at 0.2 mg/mL in sterile PBS.

• Shipping

  The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

• Stability & Storage

  Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

• 12 months from date of receipt, -20 to -70 °C as supplied.

• 1 month, 2 to 8 °C under sterile conditions after reconstitution.

• 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TREM-3

TREM-3 is a type I transmembrane protein possessing a single extracellular Ig domain. It associates with the signal adapter molecule, DAP12, and delivers an activating signal. TREM-3 mRNA was detected in macrophage cell lines and at low levels in T cell lines, but not in NK, B cell, or mast cell lines.

• Long Name:

  Triggering Receptor Expressed on Myeloid Cells 3

• Entrez Gene IDs:

  58218 (Mouse)

• Alternate Names:

  TREM3; TREM-3