• Species Reactivity

  Mouse

• Specificity

  Detects mouse Exostosin-like 2/EXTL2 Lumenal Domain in direct ELISAs and Western blots. In Western blots, less than 5% cross-reactivity with recombinant mouse EXTL1 and recombinant human EXTL3 is observed.

• Source

  Polyclonal Goat IgG

• Purification

  Antigen Affinity-purified

• Immunogen

  Mouse myeloma cell line NS0-derived recombinant mouse Exostosin-like 2/EXTL2 Lumenal Domain    
  Asn43-Met330    
  Accession # Q9ES89

• Formulation

  Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

• Label

  Unconjugated

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Western Blot

  0.1 µg/mL

  Recombinant Mouse Exostosin-like 2/EXTL2 Lumenal Domain

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Reconstitution

  Reconstitute at 0.2 mg/mL in sterile PBS.

• Shipping

  The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

• Stability & Storage

  Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

• 12 months from date of receipt, -20 to -70 °C as supplied.

• 1 month, 2 to 8 °C under sterile conditions after reconstitution.

• 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Exostosin-like 2/EXTL2

Exostosin-like proteins are transmembrane glycosyltransferases found in the endoplasmic reticulum. These proteins are involved in the biosynthesis of heparan sulfate proteoglycans. Mutations of EXTL proteins are associated with the development of multiple exostoses (benign bone growths) and cancer.

• Entrez Gene IDs:

  2135 (Human); 58193 (Mouse)

• Alternate Names:

  Alpha-1,4-N-acetylhexosaminyltransferase EXTL2; alpha-1,4-N-acteylhexosaminyltransferase; Alpha-GalNAcT EXTL2; EC 2.4.1.223; exostoses (multiple)-like 2; Exostosin like 2; Exostosin-like 2; EXTL2; EXTR2; EXT-related protein 2; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; processed exostosin-like 2