• Species Reactivity

  Mouse

• Specificity

  Detects mouse IGFBP‑rP10 in direct ELISAs and Western blots.

• Source

  Polyclonal Goat IgG

• Purification

  Antigen Affinity-purified

• Immunogen

  Mouse myeloma cell line NS0-derived recombinant mouse IGFBP‑rP10    
  Arg38-Tyr313    
  Accession # NP_849260

• Formulation

  Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

• Label

  Unconjugated

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Western Blot

  0.1 µg/mL

  Recombinant Mouse IGFBP-rP10

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Reconstitution

  Reconstitute at 0.2 mg/mL in sterile PBS.

• Shipping

  The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

• Stability & Storage

  Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

• 12 months from date of receipt, -20 to -70 °C as supplied.

• 1 month, 2 to 8 °C under sterile conditions after reconstitution.

• 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IGFBP-rP10

IGFBP-rP10, also known as Kazal-type serine protease inhibitor domain-containing protein 1 and bone and odontoblast-expressed protein 1, belongs to the IFGBP superfamily. It is a 276 amino acid (aa) residue, 36 kDa secreted protein that contains an N-terminal IGFBP domain, a Kazal-type serine protease inhibitor region, a C2-type Ig-like domain and a C-terminal poly-glu segment. An alternate variant with a 16 aa substitution for the C-terminal 33 residues has also been reported. IGFBP‑rP10 is expressed in multiple tissues including osteoblasts/odontoblasts and is up-regulated during osteoblast differentiation and bone regeneration. Mouse mature IGFBP-rP10 shares 96% and 87% aa sequence identity with rat and human IGFBP-rP10, respectively.

• Long Name:

  Insulin-like Growth Factor Binding Protein Related Protein-10

• Entrez Gene IDs:

  81621 (Human); 107250 (Mouse); 293997 (Rat)

• Alternate Names:

  bone- and odontoblast-expressed gene 1; Bono1; FKSG28; FKSG40; FLJ24094; IGFBP-related protein 10; IGFBPrP10; IGFBP-rP10; KAZALD1; Kazal-type serine peptidase inhibitor domain 1; Kazal-type serine protease inhibitor domain 1; kazal-type serine protease inhibitor domain-containing protein 1; novel kazal-type serine protease inhibitor domain and immunoglobulin domain containing protein; UNQ2945/PRO21184