• Species Reactivity

  Mouse

• Specificity

  Detects mouse IL-38/IL-1F10 in direct ELISAs.

• Source

  Monoclonal Rat IgG    _2A Clone # 798036

• Purification

  Protein A or G purified from hybridoma culture supernatant

• Immunogen

  E. coli-derived recombinant mouse IL-38/IL-1F10    
  Met1-Arg152    
  Accession # Q8R459

• Formulation

  Supplied in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 488

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Intracellular Staining by Flow Cytometry

  5 µL/10    ⁶ cells

  See below

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Data Examples

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Protect from light.    Do not freeze.    

• 12 months from date of receipt, 2 to 8 °C as supplied.

Background: IL-38/IL-1F10

IL-1F10, also known as IL-1HY2 and IL-38, is a secreted protein that shares sequence and structural similarity with IL-1 receptor antagonist and other IL-1 family members. It is expressed in basal epithelia of the skin and in proliferating germinal center CD20⁺ B cells. IL-1F10 binds soluble IL-1RI in vitro and may participate in regulation of immune responses. Mouse IL-1F10 shares 82% and 93% amino acid identity with human and rat IL-1F10, respectively. IL-1F10 is predicted to be 17 kDa.

• Long Name:

  Interleukin 1 Family Member 10

• Entrez Gene IDs:

  84639 (Human); 215274 (Mouse)

• Alternate Names:

  FIL1- theta; FKSG75; IL1F10; IL-1HY2; IL38; IL-38; interleukin 1 family, member 10 (theta); UNQ6119/PRO20041