详细说明
- Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
- Endotoxin Level<0.10 EU per 1 μg of the protein by the LAL method.
- ActivityMeasured by its binding ability in a functional ELISA. When Recombinant Human AICL/CLEC-2B Fc Chimera is coated at 2 µg/mL (100 µL/well), the concentration of Recombinant Human Galectin-1 (Catalog # 1152-GA) that produces 50% optimal binding response is 0.6-3 µg/mL.
- SourceChinese Hamster Ovary cell line, CHO-derived
MD Human IgG1
(Pro100-Lys330)IEGR Human AICL/CLEC-2B
(Lys26-His149) with a Met79Thr substitution
Accession # Q92478N-terminus C-terminus - N-terminal Sequence
AnalysisMet - Structure / FormDisulfide-linked homodimer
- Predicted Molecular Mass41 kDa
- SDS-PAGE48-65 kDa, reducing conditions
9059-CL | | |
Formulation Lyophilized from a 0.2 μm filtered solution in PBS. | ||
Reconstitution Reconstitute at 500 μg/mL in PBS. | ||
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. | ||
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Bioactivity | When Recombinant HumanAICL/CLEC-2B Fc Chimera (Catalog # |
- References:
- Li, Y. et al. (2014) Front. Immunol. 5:123.
- Hamann, J. et al. (1997) Immunogenetics 45:295.
- Welte, S. et al. (2006) Nat. Immunol. 7:1334.
- Klimosch, S.N. et al. (2013) Blood 122:2380.
- Long Name:Activation-Induced C-Type Lectin
- Entrez Gene IDs:9976 (Human)
- Alternate Names:Activation-induced C-type lectin; AICL; AICLC-type lectin superfamily member 2; CLEC2B; CLEC-2B; CLECSF2; CLECSF2IFN-alpha-2b-inducing-related protein 1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 2 (activation-induced); C-type lectin domain family 2 member B; C-type lectin domain family 2, member B; HP10085; IFN-alpha2b-inducing related protein 1; IFNRG1