详细说明
应用； A PGI2 (prostacyclin) analog and IP receptor agonist
CAS号码: 94079-80-8
纯度: ≥98%
分子量: 374.48
分子式: C22H30O5
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* 参考分析证明 大量特定数据 (包括水 含量). Cicaprost is a PGI2 analog which causes prostacyclin receptor (IP) activation. The activation of IP by this compound is associated with phosphorylation of transcription factor cAMP response element binding protein as well as cAMP elevation. Experiments suggest that Cicaprost also contains strong anti-mitogenic characteristics and can regulate the p27(kip1) levels in cells.
参考文献
1. Hildebrand, M., et al. 1990. Eur. J. Clin. Pharmacol. 39: 149-153. PMID: 2253664
2. Zhou, W., et al. 2007. J. Immunol. 178: 702-710. PMID: 17202330
3. Chan, E.C., et al. 2010. J. Mol. Cell. Cardiol. 49: 176-185. PMID: 20403362
4. Castagnino, P., et al. 2010. Prostaglandins Other Lipid Mediat. 93: 20-24. PMID: 20457271
物理状态 :
Liquid
保存 :
Store at -20° C
折射率 :
n 20 D 1.57 (Predicted)
pK值 :
pK a: 3.41 (Predicted)
仅供科研使用。不可用于诊断或治疗。
运输 :
UN 1231, Class 3, Packing group II
PubChem CID :
5311044
MDL 号码 :
MFCD00865953
SMILES :
CCC#CC[C@H](C)[C@@H](C#C[C@H]1[C@@H](C[C@H]2[C@@H]1C/C(=C/COCC(=O)O)/C2)O)O
400-6226-992