VIP会员
备注:化学品受到各种因素影响，售价会有波动，当前售价非实际售价，下单前请联系客服核实价格和运费！产品详细参数请咨询客服！
基本信息
- 利那拉生
- Linaprazan
- -20°C, 3 years; 2-8°C, 2 years.
生物活性
Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding. (IC50: 1.0 ± 0.2 μM) It is a acid-suppressing agents with rapid onset of action and potent acid inhibition. In vitro: Linaprazan can inhibit the final step in acid secretion. Linaprazanreduced porcine renal Na+,K+-ATPase activity by 9 ± 2%, demonstrating a high selectivity for H+,K+-ATPase. In vivo: The reference for animal administration is 0.5-1.0 mg/kg. The greater degree of acid suppression with the 75-mg dose of Linaprazan would translate to a healing rate of 89% at 4 weeks.
400-6226-992