20243-59-8
羟基芫花素(3,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one)
CAS: 20243-59-8;569-92-6
化学式: C16H12O6
中文名 | 羟基芫花素 |
英文名 | 3,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one |
别名 | 羟基芫花素 羟基芫花黄素 羟基芫花素对照品 羟基芫花素标准品 木犀草素7-甲基醚 7-O-甲基木犀草素 5,3',4'-三羟基-7-甲氧基黄酮 |
英文别名 | Rhamnocitrin hydroxygenkwanin hydroxyl genkwanin 7-O-Methylluteolin 3'-hydroxygenkwanin Luteolin 7-methylether 3',4',5-Trihydroxy-7-methoxyflavone 3,5-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one 3,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one 2-(3,4-Dihydroxyphenyl)-7-methoxy-5-hydroxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 3,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxy- |
CAS | 20243-59-8 569-92-6 |
化学式 | C16H12O6 |
分子量 | 300.26 |
InChI | InChI=1/C16H12O6/c1-21-10-6-11(18)13-12(7-10)22-16(15(20)14(13)19)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3 |
密度 | 1.512±0.06 g/cm3(Predicted) |
熔点 | 258-260 °C |
沸点 | 602.7±55.0 °C(Predicted) |
闪点 | 218.4°C |
蒸汽压 | 6.45E-14mmHg at 25°C |
溶解度 | DMSO: 60 mg/mL (199.82 mM) |
折射率 | 1.709 |
酸度系数 | 6.33±0.40(Predicted) |
存储条件 | 2-8°C |
外观 | 黄色粉末 |
物化性质 | 黄色结晶粉末,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于芫花。 |
MDL号 | MFCD11046350 |
体外研究 | Hydroxygenkwanin (7-O-Methylluteolin) inhibits C6 glioma cell proliferation in a dose dependent manner. Hydroxygenkwanin induces the cell cycle arrest by flow cytometry and inhibits colony formation ability and cell movement. Hydroxygenkwanin induces cell cycle arrest through p21 activation and causes intrinsic cell apoptosis pathway. |